Influence of FK506 and cyclosporin A on alloantibody production and lymphocyte activation following blood transfusion
نویسندگان
چکیده
منابع مشابه
The actions of cyclosporin A and FK506 on T-lymphocyte activation.
Introduction Activation of T-lymphocytes is a complex process requiring recognition of antigen by the T-cell antigen receptor as well as concomitant signals from the antigen-presenting cells. These events lead to the activation of second-messenger pathways such as tyrosine kinases and protein kinase C and to an increase in intracellular Ca2+ concentration [ 1-31. This initiates a sequential act...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2008
ISSN: 0009-9104
DOI: 10.1111/j.1365-2249.1990.tb05472.x